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Endocrine disruptors: An overview of latest developments at European level in the context of plant protection products

25-04-2019

Endocrine disruptors (EDs) are chemical substances present in many products of daily life, which interact with the hormonal system and can disrupt its proper functioning. There is a growing interest in understanding EDs and progress has been made on both the scientific and regulatory side, but the topic remains of high concern at decision-making and societal levels because of the challenges it still poses. This paper provides a desk-research based overview of the key moments of the (scientific and ...

Endocrine disruptors (EDs) are chemical substances present in many products of daily life, which interact with the hormonal system and can disrupt its proper functioning. There is a growing interest in understanding EDs and progress has been made on both the scientific and regulatory side, but the topic remains of high concern at decision-making and societal levels because of the challenges it still poses. This paper provides a desk-research based overview of the key moments of the (scientific and regulatory) debate on EDs, with a focus on the latest developments at European level, namely Commission Regulation (EU) 2018/605 and the 2018 Commission communication ‘Towards a comprehensive European Union framework on endocrine disruptors’, in the particular context of plant protection products (PPPs).

Endocrine Disruptors: From Scientific Evidence to Human Health Protection

15-01-2019

This study, commissioned by the PETI Committee of the European Parliament, presents the scientific knowledge regarding the health effects of endocrine disruptors, a class of hazards recognized in EU regulation since 1999. This report reviews the scientific evidence regarding the concept of endocrine disruption, the extent of exposure, associated health effects and costs. The existing relevant EU regulations are discussed and recommendations made to better protect human health.

This study, commissioned by the PETI Committee of the European Parliament, presents the scientific knowledge regarding the health effects of endocrine disruptors, a class of hazards recognized in EU regulation since 1999. This report reviews the scientific evidence regarding the concept of endocrine disruption, the extent of exposure, associated health effects and costs. The existing relevant EU regulations are discussed and recommendations made to better protect human health.

Външен автор

Barbara DEMENEIX, PhD, UMR 7221 CNRS/MNHN, Muséum National d’Histoire Naturelle, Paris, France. Rémy SLAMA, PhD, Senior Investigator, INSERM (National Institute of Health and Medical Research), IAB Research Center, Team of Environmental Epidemiology, Grenoble, France.

Parliament rejects criteria for endocrine disruptors

12-10-2017

On 4 October 2017, the European Parliament voted to object to the European Commission's draft regulation setting out criteria for identifying endocrine disruptors in the area of plant protection products (PPPs). The vote followed the Parliament's Committee on the Environment, Public Health and Food Safety (ENVI) backing a motion for resolution to reject the criteria. The Commission says it needs now to reflect on the next steps to take.

On 4 October 2017, the European Parliament voted to object to the European Commission's draft regulation setting out criteria for identifying endocrine disruptors in the area of plant protection products (PPPs). The vote followed the Parliament's Committee on the Environment, Public Health and Food Safety (ENVI) backing a motion for resolution to reject the criteria. The Commission says it needs now to reflect on the next steps to take.

Agreement on criteria for endocrine disruptors

11-07-2017

On 4 July 2017, the European Commission's Standing Committee on Plants, Animals, Food and Feed (SC PAFF), made up of experts from the EU Member States, voted on the Commission's draft regulation setting out criteria for identifying endocrine disruptors in the area of plant protection products (PPPs). The vote was preceded by several meetings in which the Commission presented revised versions of its drafts. The European Parliament and the Council of the EU now have three months to examine the agreed ...

On 4 July 2017, the European Commission's Standing Committee on Plants, Animals, Food and Feed (SC PAFF), made up of experts from the EU Member States, voted on the Commission's draft regulation setting out criteria for identifying endocrine disruptors in the area of plant protection products (PPPs). The vote was preceded by several meetings in which the Commission presented revised versions of its drafts. The European Parliament and the Council of the EU now have three months to examine the agreed text.

Food contact materials

27-09-2016

Food is considered to be one of the most important sources of human exposure to chemicals. The safety of materials coming into contact with food should therefore be carefully evaluated, as chemicals from these can migrate into food. The European Parliament’s Committee on the Environment, Public Health and Food Safety (ENVI) has drafted an own-initiative report highlighting the problems related to the implementation of the Food Contact Materials Regulation, and this is due to be debated during the ...

Food is considered to be one of the most important sources of human exposure to chemicals. The safety of materials coming into contact with food should therefore be carefully evaluated, as chemicals from these can migrate into food. The European Parliament’s Committee on the Environment, Public Health and Food Safety (ENVI) has drafted an own-initiative report highlighting the problems related to the implementation of the Food Contact Materials Regulation, and this is due to be debated during the October I plenary session.

Setting criteria on endocrine disruptors: Follow-up to the General Court judgment

27-04-2016

Endocrine disruptors are substances that interfere with the functioning of hormones, with potentially harmful effects on health. A wide range of chemicals are suspected of being responsible for endocrine-disrupting activity. Defining scientific criteria for their identification is highly complex and has important repercussions for a wide range of stakeholders. There is a lack of consensus among both scientists and regulators. Work on the issue has been conducted at EU and international level. The ...

Endocrine disruptors are substances that interfere with the functioning of hormones, with potentially harmful effects on health. A wide range of chemicals are suspected of being responsible for endocrine-disrupting activity. Defining scientific criteria for their identification is highly complex and has important repercussions for a wide range of stakeholders. There is a lack of consensus among both scientists and regulators. Work on the issue has been conducted at EU and international level. The European Commission's delay in adopting scientific criteria has provoked strong reactions from various stakeholders. The Commission is expected to come up with scientific criteria and to present the legal acts required before summer 2016. In a judgment delivered on 16 December 2015, the General Court of the Court of Justice of the EU found that the Commission had breached European Union law by failing to act on endocrine disruptors. It concluded that the Commission did not comply with its clear obligation to specify scientific criteria for the identification of chemicals that have endocrine-disrupting properties by 13 December 2013. In addition, it stated that there was no requirement to carry out an impact assessment, which the Commission had suggested was necessary to evaluate the various possible options prior to taking its decision.

EU policy on endocrine disruptors

07-03-2013

Endocrine disruptors (EDs) are substances that disturb the functioning of hormones, and are associated with various human health problems, including reduced fertility and reproductive abnormalities. EDs can act at very low doses and are especially dangerous during pregnancy and in infancy.

Endocrine disruptors (EDs) are substances that disturb the functioning of hormones, and are associated with various human health problems, including reduced fertility and reproductive abnormalities. EDs can act at very low doses and are especially dangerous during pregnancy and in infancy.

Proceedings of the Workshop on "Endocrine Disruptors and Impact on Health"

14-09-2012

This report summarises the presentations and discussions at the Workshop on Endocrine Disruptors and Health, held at the European Parliament in Brussels, on Tuesday 18 September 2012. The aim of the workshop was to better understand the impacts of endocrine disruptors on health and to provide input into the ongoing policy discussions at EU-level. The workshop was hosted and chaired by MEP Åsa Westlund (S&D, SE), Rapporteur for the Parliament’s own initiative report on the “Protection of public health ...

This report summarises the presentations and discussions at the Workshop on Endocrine Disruptors and Health, held at the European Parliament in Brussels, on Tuesday 18 September 2012. The aim of the workshop was to better understand the impacts of endocrine disruptors on health and to provide input into the ongoing policy discussions at EU-level. The workshop was hosted and chaired by MEP Åsa Westlund (S&D, SE), Rapporteur for the Parliament’s own initiative report on the “Protection of public health from endocrine disruptors”.

Външен автор

Gustaaf Borchardt (European Commission, DG Environment) , Tapani Piha (European Commission, DG SANCO) , Jacqueline McGlade (European Environment Agency) , Peter Korytar (European Commission, DG Environment) , Jim Bridges (Univ. of Surrey) , Andreas Kortenkamp (Institute for the Environment, Brunel University, London) , Alberto Mantovani (National Health Institute of Health, ISS, Italy) , Peter Smith (Programme Product Stewardship, CEFIC) and Yannick Vicaire (Réseau Environment Santé, RES)

Health threats from endocrine disruptors: A scientific and regulatory challenge

12-06-2012

Endocrine disruptors are substances that disturb the functioning of hormones and have negative effects on human health and wildlife. Despite intense research efforts, there are still major gaps in understanding of endocrine disruption phenomena.

Endocrine disruptors are substances that disturb the functioning of hormones and have negative effects on human health and wildlife. Despite intense research efforts, there are still major gaps in understanding of endocrine disruption phenomena.

The benefits of strict cut-off criteria on human health in relation to the proposal for a Regulation concerning plant protection products

15-09-2008

Executive Summary This study assesses the health benefits of strict ‘cut-off criteria’ on human health in relation to the proposal for a Regulation concerning the placing of plant protection products on the market (COM(2006) 388). The Common Position text provides that active substances classified as carcinogen, mutagen or toxic for reproduction category 1 or 2 (CMR 1 & 2), or substances considered to have endocrine disrupting properties (ED) on the basis of internationally agreed test guidelines ...

Executive Summary This study assesses the health benefits of strict ‘cut-off criteria’ on human health in relation to the proposal for a Regulation concerning the placing of plant protection products on the market (COM(2006) 388). The Common Position text provides that active substances classified as carcinogen, mutagen or toxic for reproduction category 1 or 2 (CMR 1 & 2), or substances considered to have endocrine disrupting properties (ED) on the basis of internationally agreed test guidelines, shall not be approved unless exposure to humans under realistic proposed conditions of use would be negligible. The European Parliament in its first reading amendments proposed the additional criteria that substances “considered to cause a risk of developmental neurotoxic or immunotoxic properties in humans, taking into account exposure during embryonic/foetal life and/or during childhood as well as likely combination effects” should only be approved if human exposure would be negligible. In view of the continuing debate about the criteria for approval of active substances, this study provides a scientific review of evidence concerning human health effects of plant protection products, including health benefits that could accrue from the stricter cut-off criteria. The study supports the proposal of the European Parliament that in order to ensure added protection of human health, substances considered to cause a risk of developmental neurotoxic or immunotoxic effects in humans should be added to the list of classifications that would result in non-approval of active substances, unless negligible exposure can be demonstrated. The emerging epidemiological evidence for these effects will need to be translated into classification criteria before harmonised classification for these effects can be achieved. Given that many CMR3 substances may be reclassified at a future point as CMR2, the additional proposal of the European Parliament to include CMR3 as criteria for

Външен автор

Mark Blainey, Catherine Ganzleben, Gretta Goldenman and Iona Pratt (MILIEU Ltd. - Brussels)

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